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Table 2. Baseline demographic data, presentation of 104 patients with malignant pleural effusion

From: Chemical pleurodesis for malignant pleural effusion: which agent is perfect?

Characteristic

Mean ± SD

n

Range

%

Age (mean ± SD, range), years

57.55 ± 9.02

22–74

Male, n (%)

50

48.1

Diabetes mellitus

24

23.7

Hypertension

57

54.8

Congestive heart failure

13

12.5

Hepatic dysfunction

8

7.7

Smoker

28

26.9

Side of intervention, right, n (%)

59

56.7

ECOG score, n (%)

  

 0–2

80

76.9

 3–4

21

20.2

 Unknown

3

2.9

Effusion grade

  

 Small (1–2)

0

0

 Moderate (3–4)

6

5.8

 Large (5)

26

25

 Massive (6)

72

69.2

Presenting symptom*

  

 Dyspnea

104

100

 Chest pain

32

30.7

 Cough

39

37.5

 Chest pain and cough

24

23.1

Dyspnea score (NYHA)

  

 NYHA II

9

8.7

 NYHA III

36

34.6

 NYHA IV

59

56.7

Pleural fluid chemistry

  

 Exudate

104

100

 Mean PH

7.14 ± 0.22

6.87–7.48

 PH < 7.3

93

89.4

 PH ≥ 7.3

11

10.6

 Glucose (mg/dl)

73.3 ± 25.1

24–119

 LDH (IU/L)

1493± 294

586–2862

Pleural fluid cytology

  

 WBC (/μl)

624.2± 58

300–2216

 Mono (%)

73.4± 3.6

65–87

 Malignant (%)

12.3± 5.2

4–28

 RBC (/μl)

19560± 58.7

1400–4800

  1. Eastern Cooperative Oncology Group (ECOG) performance status score runs from 0 to 5, where 0 is fully active, 1 is restricted in physical strenuous activity, 2 is unable to carry out any work activities, 3 is only able to carry out limited self-care activities, 4 is completely disabled, and 5 is dead
  2. Baseline effusion size was graded on chest radiograph immediately prior to trial intervention, using a validated grading system whereby grade 0 referred to no radiographic evidence of pleural fluid; grade 1, blunting of the costophrenic angle; grade 2 to 5, fluid occupying less than 25%, 25% to 50%, 51% to 75%, and more than 75% of the hemithorax, respectively
  3. *The presenting symptoms are non-mutually exclusive