Table 4 Review of the literature concerning mitral valve repair in IE
From: Feasibility and outcome of mitral valve repair in patients with infective endocarditis
First author, year | Study design | Number of patients | Repair | Replacement | Infected valve | Primary endpoints | Secondary endpoints | Results |
|---|---|---|---|---|---|---|---|---|
Hendren W.G. et al., 1992 [1] | Retrospective single-center cohort study | 22 | 22 | 0 | Mitral | Clinical results of repair | In-hospital mortality | Mitral repair had a low mortality and no reinfections. |
Podesser B.K. et al., 2000 [2] | Retrospective single-center cohort study | 22 | 22 | 0 | Mitral | Survival rate at 1–5 years | In-hospital mortality | Mitral valve repair in IE had a low incidence of complications and a good medium-term survival. |
Feringa H.H. et al., 2007 [3] | Systematic review | 1194 | 470 | 724 | Mitral | Morbidity and mortality | Repair had lower early and late mortality, less reoperations, lower rate of adverse events. | |
Ishikawa S. et al., 2008 | Retrospective single-center cohort study | 40 | 4 | 31 | Mitral and aortic valves | Intra-operative results | In-hospital mortality | Good operative results after infective sites resection. |
Huang X.S. et al., 2009 [5] | Retrospective observational study | 40 | 39 | 1 | Mitral | Clinical and echocardiographic results of repair | In-hospital mortality | Good clinical results of mitral repair with favorable atrial and ventricular remodeling and valvular function. |
Omoto T. et al., 2011 [6] | Retrospective single-center cohort study | 22 | 15 | 7 | Mitral | In-hospital mortality | Survival rate at 1–5 years | Mitral valve repair in IE is feasible and is associated with a larger reduction of end diastolic ventricular volume. Concerns about durability of large resection. |
Evans C.F. et al., 2011 [7] | Systematic review | Event-free survival | Repair was associated with lower mortality (< 10%), better survival rate (> 80% at 5 years), lower relapse rate, and neurologic complications. | |||||
De Kerchove et al., 2012 [22] | Retrospective single-center cohort study | 137 | 109 | 28 | Mitral | Hospital mortality | Freedom from mitral valve repair failure | Hospital mortality was 16%. At 8 years, overall survival was 62% ± 10% with no differences between patients with or without patch repair (p = .5). Freedom from mitral valve repair failure was 81% ± 14% in patients with patch repair and 90% ± 10% in patients without patch repair (p = .09). |
Chang H.W. et al., 2014 [8] | Retrospective single-center cohort study | 26 | 11 | 6 | In-hospital mortality | No patients had residual regurgitation post-operatively nor at follow-up. None in-hospital death. | ||
Zhao D. et al., 2014 [11] | Systematic review | Mitral and aortic valves | Morbidity and mortality | Event-free survival | Repair had a better overall survival and event-free survival. | |||
Mick S.L. et al., 2015 [12] | Systematic review | Mitral | Mortality | Valve repair had a lower in-hospital and long-term mortality and lower risk of neurological events and relapse. | ||||
Rostagno C. et al., 2017 [13] | Retrospective single-center cohort study | 34 | 34 | 0 | Mitral | Survival rate at 1–5 years | Event-free survival rate | Repair was associated with good long-term results. |
Toyoda et al., 2017 [23] | Retrospective multicentric study | 1979 | 367 | 1603 | Mitral | Long-term survival | Recurrent endocarditis and mitral reoperation | Repair is associated with better survival and lower risk of recurrent infection. |
Hu Y.N. et al., 2018 [14] | Systematic review | 779 | 779 | 0 | Mitral | Mortality | Short-term mortality after mitral repair in IE was 6%; freedom from reintervention was > 90% at 5 years and > 85% at 10 years. Long-term results support adequate durability of repair. | |
Liu J.Z. et al., 2018 [15] | Meta-analysis | 633 | 265 | 368 | Mitral | Operative mortality. Survival rate at 1–5 years | Post-operative results | Good post-operative results and survival. |
Solari S. et al., 2018 [17] | Retrospective single-center cohort study | 192 | 155 | 37 | Mitral | Overall survival. Event-free survival | Repair had a good durability and low rate of IE relapse. | |
Harky A. et al., 2018 [18] | Meta-analysis | 8978 | 2906 | 6072 | Mitral | Morbidity and mortality | Repair had lower relapse rate, better event-free survival, and overall survival at 1–5 years. | |
Lee HA et al., 2018 [19] | Retrospective multicenter study | 1999 | 424 | 1575 | Mitral | Morbidity and mortality | Mitral repair for IE has better perioperative and late outcomes than mitral replacement. | |
Okada y et al., 2020 [20] | Retrospective single-center study | 171 | 147 | 24 | Mitral | Survival, freedom from reoperation, and event-free survival | Mitral valve repair was highly successful using autologous pericardium, chordal reconstruction, and ring annuloplasty if required. Long-term results were acceptable. | |
Defauw RJ et al., 2020 [21] | Retrospective single-center study | 149 | 97 | 52 | Mitral | Survival | Recurrence, reintervention | Beyond 1 year post-surgery, replacement was associated with decreased survival. |