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Table 1 General characteristics and outcomes of included studies

From: Efficacy of heart transplantation in patients with a failing Fontan: a systematic review and meta-analysis

Study ID (author, year)

Region

Type of study and design

Study follow-up time

Number of patients who underwent heart transplantation (n)

Mean agea (years)

Males (%)

1-year survival (n)

5-year survival (n)

Acute rejection (n)

Sepsis (n)

Renal failure (n)

Multi-organ dysfunction (n)

Christopher J. Berg, 2017 [10]

USA

Retrospective, single center

1991–2014

36

21.3 (7.2–48.1)

61

27

18

5

-

7

-

Luiz Fernando Caneo, 2017 [11]

Brazil

Retrospective, single center

1984–2015

8

8 (6-12)

-

-

5

-

-

8

-

Chiara Marrone, 2017 [12]

Italy

Retrospective, single center

8.7 years

23

17.6 (11–33)

65

17

19

2

1

-

1

Jonathan N Menachem, 2017 [13]

USA

Retrospective, single center

2010–2016

8

40 (23–57)

50

8

-

-

-

-

-

Daphne T. Hsu, 1995 [14]

USA

Retrospective, single center

1984–1993

9

13.6

-

6

6

1

4

-

-

Amando Gamba, 2004 [15]

Italy

Retrospective, single center

1990–2002

14

17.6 (5.3–33.8)

50

12

9

6

1

-

1

Milind Chaudhari, 2005 [16]

UK

Retrospective, single center

1985–2003

4

6.78

83.30

3

3

1

1

-

-

Jacob Simmonds, 2008 [17]

UK

Retrospective, single center

1988–2007

15

-

-

11

9

-

-

-

-

C Irving, 2010 [18]

UK

Retrospective, Single center

1988–2009

3

23.8 (20.8–27)

-

2

2

-

1

-

1

Joshua R Kovach, 2012 [19]

UK/USA/Canada

Retrospective, multi-center

1993–2008

194

10.3 (0.4–18.2)

64

155

136

-

-

15

-

Paniagua Martin, 2012 [20]

Spain

Retrospective, multi-center

1984–2009

10

19 (10)

50

6

-

-

-

-

-

Franceso Seddio, 2013 [21]

Italy

Retrospective, single center

1985–2011

22

-

-

19

0

1

1

-

1

E Delmo Walter, 2013 [22]

Germany

Retrospective, Single center

1986–2011

5

6.6 (2–14 )

-

2

0

1

-

-

-

Santuri Rungan, 2014 [23]

New Zealand

Retrospective, single center

1987–2012

6

16 (6–33)

100

6

6

4

0

0

-

Jay J. Iyengar, 2014 [24]

Australia

Retrospective, single center

1988–2013

8

12.37

53.80

8

7

-

-

-

-

Guido Michielon, 2015 [25]

Europe, USA

Retrospective, multi-center

1991-2011

61

15 ± 9.7

63.90

51

45

1

22

-

5

  1. aThe numbers in brackets for mean age show minimum to maximum