Table 3 Index of deterioration versus EuroScore values
From: Index of deterioration of patients with mechanical prosthetic heart valve thrombosis
Index of deterioration (ID) | EuroScore II | |||
|---|---|---|---|---|
Variable | Effect size | P value | Effect size | P value |
A-Preoperative (on admission) | ||||
Age (years) | r = −0.245 | 0.023 | r = 0.039 | 0.73 |
Gender | ||||
Females versus males | 0.55 (0.07-3) vs. 0.21 (0.03-1.5) | 0.003 | 8.4 (2.9-26.5) vs. 5 (1.69-15) | 0.13 |
Non-pregnant females vs. males* | 0.46 (0.07-1.5) vs. 0.23 (0.03-1.5) | 0.05 | 8.4 (2.9-26.5) vs. 5 (1.69-15) | 0.27 |
Pregnancy: pregnant vs. other cases | 0.87 (0.3-3) vs. 0.39 (0.03-1.5) | 0.003 | 8.4 (3.4-11.2) vs. 6.5 (1.7-26.5) | 0.13 |
Position | ||||
Mitral + tricuspid | 2 (2-2) | 11.5 (7.9-15) | ||
Mitral + aorta | 1 (0.07-1) | 6.6 (6.4-10.5) | ||
Single mitral | 0.46 (0.07-3) | 6.9 (2.8-18) | ||
Single aortic | 0.3 (0.03-1) | 0.43 | 6.4 (1.7-26.5) | 0.47 |
Non-compliance to OAC: yes vs. no | 0.5 (0.1-3) vs. 0.33 (0.03-1.5) | 0.03 | 6.9 (2.8-18) vs. 6.4 (1.7-26.5) | 0.36 |
Thromboembolic events: yes vs. no | 0.29 (1-1.5) vs. 0.5 (0.03-3) | 0.35 | 8.4(2.9-11.4) vs. 6.6 (1.7-26.5) | 0.99 |
LVEF% at presentation | r = −0.155 | 0.155 | r = −0.44 | < 0.001 |
Mean gradient across prosthesis | ||||
Mitral | r = 0.52 | < 0.001 | r = 0.325 | 0.007 |
Aortic (mm Hg)** | r = −0.44 | 0.129 | r = −0.53 | 0.061 |
NYHA functional class | ||||
Class II | 0.1 (0.03-0.14) | 2.86 (1.69-3.7) | ||
Class III | 0.17 (0.03-2) | 3.7 (2.77-11.95) | ||
Class IV | 0.75 (0.14-3) | < 0.001 | 8.44 (3.72-26.5) | < 0.001 |
Latent period (months) | r = −0.489 | < 0.001 | r = −0.228 | 0.035 |
Manifest period (days) | r = −0.974 | < 0.001 | r = −0.478 | < 0.001 |
Schedule of surgery | ||||
Emergency (n = 50) | 0.6 (0.1-3) | 8.44 (3.72-26.5) | ||
Urgent (n = 45) | 0.17 (0.03-1) | 3.73 (2.77-10.65) | ||
Elective (n = 5) | 0.088 (0.03-0.14) | < 0.001 | 2.53 (1.69-3.38) | < 0.001 |
B-Operative and postoperative | ||||
Aortic cross clamp time (min) | r = 0.17 | 0.12 | r = 0.204 | 0.06 |
Cardiopulmonary bypass time (min) | r = 0.66 | 0.013 | r = 0.35 | 0.001 |
Mechanical ventilation | r = 0.31 | 0.004 | r = 0.219 | 0.043 |
Inotropes duration (h) | r = 0.23 | 0.031 | r = 0.165 | 0.128 |
ICU stay (days) | r = 0.18 | 0.09 | r = 0.17 | 0.12 |
Total hospital stay (days) | r = 0.035 | 0.75 | r = 0.03 | 0.79 |
Postoperative LVEF% | r = −0.252 | 0.019 | r = −0.424 | < 0.001 |
Mean gradient across prosthesis | ||||
Mitral | r = 0.33 | < 0.006 | r = −0.308 | 0.011 |
Aortic (mm Hg)* | r = −0.511 | 0.075 | r = −0.302 | 0.316 |
Mortality | ||||
Mortalities (n = 18) | 0.75 (0.1-3) | 8.5 (4.2-26.5) | ||
Survivors (n = 68) | 0.35 (0.03-2) | 0.002 | 6.27 (1.69-13.84) | < 0.001 |
Hospital survivors: | ||||
Complicated (n = 29) | 0.5 (0.1-1.5) | 6.89 (2.86-13.84) | ||
Uneventful cases (n = 39) | 0.2 (0.03-2) | 0.011 | 4.4 (1.69-13.84) | 0.006 |