Table 4 Analysis of mortality

A-Preoperative

 Age (years)

39 (24-74)

49.5 (16-64)

0.21

 Female gender

40 (58.8%)

11 (61.1%)

0.86

 Pregnant patients

12 (17.6%)

4 (22.3%)

0.9

 Position of malfunctioning prosthesis

  Mitral

58 (85.3%)

15 (83.3%)

  Aortic

10 (14.7%)

3 (16.7%)

0.86

 NC-OAC (n = 47)

40 (50.6%)

13 (61.9%)

0.36

 Thromboembolic events

8 (11.8%)

4 (22.2%)

0.26

 NYHA class on admission

  Class II

3 (4.4%)

0

  Class III

34 (50%)

2 (11.1%)

0.004

  Class IV

31 (45.6%)

16 (88.9%)

0.003

 Numerical NYHA class*

3 (2-4)

4 (2-4)

 LPM (months)

48 (4-365)

36 (0.8-121.7)

0.225

 MPM (days)

8.5 (2-60)

3.5 (2-21)

0.006

 LVEF% at presentation

60 (40-73)

44.5 (22-66)

0.007

 Mean pressure gradient across mitral prosthesis (mm Hg)**

15 (9-43)

21 (12-30)

0.027

 Mean pressure gradient across aortic prosthesis (mm Hg)**

67 (45-80)

35 (25-50)

0.018

 INR on admission

1.5 (0.7-3.4)

1.8 (1-4.4)

0.078

 Serum creatinine on admission (mg/dl)

1.35 (0.8-4.2)

1.55 (1-3.4)

0.026

 SGOT on admission (units/liter)

40 (15-120)

72.5 (24-150)

0.002

 Schedule of surgery

  Emergency (n = 50)

37 (54.4%)

14 (77.8%)

  Urgent (n = 45)

29 (42.6%)

4 (22.2%)

  Elective (n = 5)

2 (2.9%)

0

0.18

 Operative procedure

  Replacement with a mechanical valve

55 (80.9%)

14 (77.8%)

  Replacement with a tissue valve

13 (19.1%)

3 (16.7%)

  Limited procedure without replacement

0

1 (5.6%)

0.37

 Aortic cross clamp time (min)

60 (37-140)

87.5 (50-200)

0.02

 Cardiopulmonary bypass time (min)

102 (55-205)

160 (100-360)

< 0.001

 Mechanical ventilation duration (h)**

24 (8-120)

33.5 (6-168)

0.54

 Inotropes duration (h)***

48 (6-168)

33.5 (12-216)

0.031

 Postoperative LVEF%***

55 (40-70)

37.5 (15-45)

< 0.001

 ICU stay (days)***

4 (1.5-14)

2.5 (2-39)

0.025

 Total hospital stay (days)***

10 (6-21)

3.5 (1-40)

< 0.001