Does prophylactic low-dose amiodarone decrease the incidence of postoperative atrial fibrillation after coronary artery bypass graft surgery? A randomized controlled trial

The Cardiothoracic Surgeon

Table 2 Outcomes in both groups

	Placebo group (n = 75)	Amiodarone group (n = 75)	P value
POAF	25 (33.3%)	12 (16%)	0.013*
Time of onset of POAF (days)	2.19 ± 0.87	2.32 ± 0.47	0.243
Patients responded to medication	12 (16%)	7 (9%)	0.22
Elapsed time to respond to medication (h)	15.77 ± 5.64	14.65 ± 3.14	0.135
Maximum ventricular rate	137.14 ± 7.21	135.25 ± 7.32	0.113
Postoperative EF (%)	43.06 ± 5.10	44.63 ± 5.81	0.081
ICU stay (days) (same)	3.31 ± 1.83	2.51 ± 1.11	0.002*
Hospital stay (days) (same)	12.72 ± 2.23	10 ± 1.99	< 0.001*

Data presented as mean ± SD or frequency (%)
AF atrial fibrillation, POAF postoperative atrial fibrillation, ICU intensive care unit, EF ejection fraction, RR Relative risk
*Significant P value < 0.05