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Table 3 Comparison between preoperative and postoperative laboratory investigations in the three groups

From: Cardioprotective effect of propofol in cardioplegia compared to systemic propofol in heart valves surgery; a randomized controlled trial

 

Laboratory investigations

Preoperative (n = 50)

Postoperative (n = 50)

P

Group 1

Creatinine

0.88 ± 0.22

0.92 ± 0.17

0.302

Urea

18.18 ± 5.24

21.48 ± 5.72

0.001*

S. albumin

3.91 ± 0.34

3.79 ± 0.40

0.097

SGPT

29.16 ± 11.72

24.26 ± 5.73

0.068

SGOT

26.56 ± 8.98

28.54 ± 5.45

0.068

Hb

12.38 ± 1.33

10.17 ± 0.94

 < 0.001*

Platelet

263.18 ± 62.13

257.24 ± 61.62

0.648

TLC

6724 ± 1603

6961 ± 1820.8

0.432

Group 2

Creatinine

0.90 ± 0.23

0.93 ± 0.16

0.425

Urea

21.48 ± 5.72

23.40 ± 6.30

0.060

S. albumin

4.13 ± 0.38

3.84 ± 0.33

 < 0.001*

SGPT

28.80 ± 12.11

29.06 ± 9.57

0.348

SGOT

26.66 ± 10.45

28.86 ± 10.10

0.043*

Hb

13.15 ± 1.19

10.13 ± 0.97

 < 0.001*

Platelet

253.10 ± 59.07

237.68 ± 56.03

0.181

TLC

6834 ± 1703.6

6609 ± 1776.14

0.545

Group 3

Creatinine

0.89 ± 0.22

0.88 ± 0.22

0.822

Urea

20.40 ± 4.69

21.48 ± 5.72

0.382

S. albumin

3.93 ± 0.33

3.77 ± 0.41

0.039*

SGPT

29.16 ± 11.72

28.80 ± 12.11

0.811

SGOT

26.56 ± 8.98

26.66 ± 10.45

0.608

Hb

12.38 ± 1.33

10.17 ± 0.87

 < 0.001*

Platelet

263.18 ± 62.13

237.12 ± 58.16

0.029*

TLC

6890 ± 1657.7

6834 ± 1703.6

0.831

  1. Data are presented as mean ± SD. SGPT Serum glutamic pyruvic transaminase, SGOT Serum glutamic oxaloacetic transaminase, Hb Hemoglobin, TLC Total leucocytic count. * P < 0.05 is statistically significant
  2. Group 1: Patients with propofol in the cardioplegia, Group 2: Patients with propofol injection in the aortic line, Group 3 (control group): Patients without propofol in the cardioplegia or aortic line