Table 2 Laboratory variables of the patients studied

Hemoglobin(gm/L)

98.5(86.5,110.5)

106(93,118)

91(80,102)

< 0.001

Platelet count (10ˆ⁹/L)

86(50.5,159.5)

101(61,178)

69(43,144)

0.011

Base excess(mmol/L)

− 6.8(− 10.4, − 4.6)

− 6.4(− 10.2, − 4.6)

− 7.6(− 11.2, − 5.3)

0.12

Blood HCO3 (mmol/L)

18.6(15.7,20.45)

18.8(16.7,20.6)

18.4(14.5,20.4)

0.27

ALT (units/L)

37.85(22.25,139.6)

37.1(23,96.1)

42.8(21.2,198.9)

0.58

AST (units/L)

119.05(54.65,270.4)

119(54.7,247.8)

119.1(54.6,315.7)

0.54

Serum creatinine (μmol/L)

105(67,147)

99(66,132)

119(75,155)

0.119

GFR (mL/min/1.73 m²)

54.5(42,60)

60(44,60)

49(39,60)

0.004

Serum bilirubin (μmol/L)

32(17.45,67.85)

28.8(15.8,42.9)

56.5(21.6,132.9)

< 0.001

INR

1.7(1.4,2.3)

1.7(1.4,2.2)

1.8(1.5,2.4)

0.12

Initial blood lactate (mmol/L)

8.45(5.7,12.15)

7(5.6,11.2)

9.5(6.2,13.5)

0.04

Lactate at 12 h (mmol/L)

8.8(4.9,15.4)

5.9(4.4,14.2)

8.7(5.3,17)

0.032

Lactate at 24 h (mmol/L)

4.6(2.4,11.95)

3.2(2.2,10)

4.5(2.7,13.5)

0.041

Peak lactate (mmol/L)

16.5(11.9,25)

14.7(10.8,25)

16.8(13.8,25)

0.11

Lactate clearance % (LC-T12)

8.39% (− 28.46,35)

26.29% (− 18.04,35.42)

4.35% (− 34.71,33.83)

0.016

Lactate clearance % (LC-T24)

42.17% (− 18.99,65.54)

44.64% (− 19.64,64.56)

28.24% (− 18.34,68.97)

0.023